Anti-MYO1D antibody (825-874) (STJ94313)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MYO1D. AA range:825-874
General Information
| Short Description | Rabbit polyclonal anti-Unconventional myosin-Id (825-874) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYO1D |
| Gene ID | 4642 |
| Uniprot ID | MYO1D_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYO1D. AA range:825-874 |
| Immunogen Region | 825-874 |
| Specificity | Myosin Id Polyclonal Antibody detects endogenous levels of Myosin Id protein. |
Additional Info
| Tissue Specificity | Expressed in many tissues. Highest levels in brain, followed by lung and ovary.expression is lowest in spleen. |
| Function | Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells. |
| Protein Name | Unconventional Myosin-Id |
| Database Links | |
| Cellular Localisation | CytoplasmPerikaryonCell ProjectionDendriteEarly EndosomeCell CortexColocalizes With The Actin Cytoskeleton In The Cell Cortex Close To The Apical Cell MembraneColocalizes With Cytoplasmic Puncta That Are Reminiscent Of Transport Vesicles |
| Alternative Antibody Names | Anti-Unconventional Myosin-Id antibodyAnti-MYO1D antibodyAnti-KIAA0727 antibody |
Information sourced from Uniprot.org