| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Unconventional myosin-XVIIIb (1680-1760 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MYO18B |
| Gene ID: | 84700 |
| Uniprot ID: | MY18B_HUMAN |
| Immunogen Region: | 1680-1760 aa |
| Specificity: | MY18B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 1680-1760 |
| Function | May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression.restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth. |
| Protein Name | Unconventional Myosin-Xviiib |
| Cellular Localisation | CytoplasmNucleusMyofibrilSarcomerePunctate Pattern In Undifferentiated MyoblastsNuclearOn Primary Cardiomyocytes And Adult MuscleA Partial Sarcomeric Location Was Found In Some Cardiomyocytes |
| Alternative Antibody Names | Anti-Unconventional Myosin-Xviiib antibodyAnti-MYO18B antibody |
Information sourced from Uniprot.org