| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MYMK (120-221) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYMK |
| Gene ID: |
389827 |
| Uniprot ID: |
MYMK_HUMAN |
| Immunogen Region: |
120-221 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 120-221 of human MYMK (NP_001073952.1). |
| Immunogen Sequence: |
GPIGTAILIIAAKWLQKMKE KKGLYPDKSVYTQQIGPGLC FGALALMLRFFFEDWDYTYV HSFYHCALAMSFVLLLPKVN KKAGSPGTPAKLDCSTLCCA CV |
| Post Translational Modifications | Palmitoylated at the C-terminus.palmitoylation promotes localization to the Golgi apparatus. |
| Function | Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of MYMX. Acts independently of MYMX. Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers. Also involved in skeletal muscle hypertrophy, probably by mediating the fusion of satellite cells with myofibers. |
| Protein Name | Protein MyomakerMyoblast Fusion MakerTransmembrane Protein 226Transmembrane Protein 8c |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneLocalizes On The Plasma Membrane Of MyoblastsWhere It Mediates Myoblasts FusionAlso Localizes In The Golgi Apparatus And Post-Golgi Following PalmitoylationThe Role Of Golgi Localization Is Unclear |
| Alternative Antibody Names | Anti-Protein Myomaker antibodyAnti-Myoblast Fusion Maker antibodyAnti-Transmembrane Protein 226 antibodyAnti-Transmembrane Protein 8c antibodyAnti-MYMK antibodyAnti-TMEM226 antibodyAnti-TMEM8C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
