Anti-MVD antibody (250-350) [S4MR] (STJ11102714)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MVD (250-350) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MVD |
| Gene ID | 4597 |
| Uniprot ID | MVD1_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | PSFAQLTMKDSNQFHATCLD TFPPISYLNAISWRIIHLVH RFNAHHGDTKVAYTFDAGPN AVIFTLDDTVAEFVAAVWHG FPPGSNGDTFLKGLQVRPAP L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MVD (P53602). |
Additional Info
| Tissue Specificity | Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. |
| Function | Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. |
| Protein Name | Diphosphomevalonate DecarboxylaseMevalonateDiphosphodecarboxylaseMddaseMevalonate Pyrophosphate Decarboxylase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168Reactome: R-HSA-446199 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Diphosphomevalonate Decarboxylase antibodyAnti-Mevalonate antibodyAnti-Diphosphodecarboxylase antibodyAnti-Mddase antibodyAnti-Mevalonate Pyrophosphate Decarboxylase antibodyAnti-MVD antibodyAnti-MPD antibody |
Information sourced from Uniprot.org