• Immunofluorescence analysis of U2OS cells using MUTYH antibody (STJ11103855). Blue: DAPI for nuclear staining.

Anti-MUTYH antibody (1-265) (STJ11103855)

SKU:
STJ11103855

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adenine Dna Glycosylase (1-265) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MUTYH
Gene ID: 4595
Uniprot ID: MUTYH_HUMAN
Immunogen Region: 1-265
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human MUTYH (NP_001041636.1).
Immunogen Sequence: MTPLVSRLSRLWAIMRKPRA AVGSGHRKQAASQEGRQKHA KNNSQAKPSACDGLARQPEE VVLQASVSSYHLFRDVAEVT AFRGSLLSWYDQEKRDLPWR RRAEDEMDLDRRAYAVWVSE VMLQQTQVATVINYYTGWMQ KWPTLQDLASASLEEVNQLW AGLGYYSRGRRLQEGARKVV EELGGHMPRTAETLQQLLPG VGRYTAGAIASIAFGQATGV VDGNVARVLCRVRAIGADP
Function Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Protein Name Adenine Dna Glycosylase
Muty Homolog
Hmyh
Database Links Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-110357
Reactome: R-HSA-9608287 Q9UIF7-3
Reactome: R-HSA-9608290
Cellular Localisation Nucleus
Mitochondrion
Alternative Antibody Names Anti-Adenine Dna Glycosylase antibody
Anti-Muty Homolog antibody
Anti-Hmyh antibody
Anti-MUTYH antibody
Anti-MYH antibody

Information sourced from Uniprot.org

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