| Short Description : | Goat polyclonal antibody anti-MUNC18C (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 70kDa band observed in Mouse and Rat Spleen lysates (calculated MW of 68.0kDa according to Rat NP_446089.1). Recommended concentration: 0.3-1µg/ml. |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | STXBP3 |
| Gene ID: | 6814 |
| Uniprot ID: | STXB3_HUMAN |
| Accession Number: | NP_009200.2 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | SKSIRRCKEINIS |
| Post Translational Modifications | Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4. |
| Function | Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. |
| Protein Name | Syntaxin-Binding Protein 3Platelet Sec1 ProteinPspProtein Unc-18 Homolog 3Unc18-3Protein Unc-18 Homolog CUnc-18c |
| Database Links | Reactome: R-HSA-114516Reactome: R-HSA-1445148 |
| Cellular Localisation | CytoplasmCytosolCell MembraneIn PlateletsPredominantly CytosolicLow Amounts Membrane-Associated |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 3 antibodyAnti-Platelet Sec1 Protein antibodyAnti-Psp antibodyAnti-Protein Unc-18 Homolog 3 antibodyAnti-Unc18-3 antibodyAnti-Protein Unc-18 Homolog C antibodyAnti-Unc-18c antibodyAnti-STXBP3 antibody |
Information sourced from Uniprot.org
