Anti-MTNR1B antibody (C-Term) (STJ71795)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MTNR1B (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave approx.48kDa and 37kDa bands in Human Brain (Cerebellum) lysates after 1ยตg/ml antibody staining. Please note that currently we cannot find an explanation i |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MTNR1B |
| Gene ID | 4544 |
| Uniprot ID | MTR1B_HUMAN |
| Accession Number | NP_005950.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | QDASKGSHAEGLQSP |
Additional Info
| Function | High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
| Protein Name | Melatonin Receptor Type 1bMel-1b-RMel1b Receptor |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melatonin Receptor Type 1b antibodyAnti-Mel-1b-R antibodyAnti-Mel1b Receptor antibodyAnti-MTNR1B antibody |
Information sourced from Uniprot.org