Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MTMR8 (430-560) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MTMR8 |
Gene ID: |
55613 |
Uniprot ID: |
MTMR8_HUMAN |
Immunogen Region: |
430-560 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2). |
Immunogen Sequence: |
HVFSCQFGNFLGNCQKDRED LRVYEKTHSVWPFLVQRKPD FRNPLYKGFTMYGVLNPSTV PYNIQFWCGMYNRFDKGLQP KQSMLESLLEIKKQRAMLET DVHELEKKLKVRDEPPEEIC TCSQLGNILSQ |
Function | Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. In complex with MTMR9, negatively regulates autophagy. |
Protein Name | Myotubularin-Related Protein 8Phosphatidylinositol-3 -5-Bisphosphate 3-PhosphatasePhosphatidylinositol-3-Phosphate Phosphatase |
Database Links | Reactome: R-HSA-1660499 |
Cellular Localisation | Nucleus Envelope |
Alternative Antibody Names | Anti-Myotubularin-Related Protein 8 antibodyAnti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-MTMR8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance