Anti-MTMR12 antibody (523-573 aa) (STJ196137)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MTMRC at the amino acid range 523-573
General Information
| Short Description | Rabbit polyclonal anti-Myotubularin-related protein 12 (523-573 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTMR12 |
| Gene ID | 54545 |
| Uniprot ID | MTMRC_HUMAN |
| Immunogen | Synthesized peptide derived from the human MTMRC at the amino acid range 523-573 |
| Immunogen Region | 523-573 aa |
| Specificity | This antibody detects endogenous levels of MTMRC at Human/Mouse/Rat |
Additional Info
| Function | Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis. |
| Protein Name | Myotubularin-Related Protein 12Inactive Phosphatidylinositol 3-Phosphatase 12Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit3-Pap3-Phosphatase Adapter Protein |
| Database Links | Reactome: R-HSA-1660516 |
| Cellular Localisation | CytoplasmSarcoplasmic ReticulumMyofibrilSarcomereLocalizes To Punctate Vesicles When Associated With Mtm1Localizes To TriadsA Structure Formed By A T Tubule And Two Sarcoplasmic Reticulum Terminal CisternaIn Skeletal MusclesCo-Localizes With Mtm1 In The SarcomerePartially Localizes To The Sarcoplasmic Reticulum In Skeletal Muscles |
| Alternative Antibody Names | Anti-Myotubularin-Related Protein 12 antibodyAnti-Inactive Phosphatidylinositol 3-Phosphatase 12 antibodyAnti-Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit antibodyAnti-3-Pap antibodyAnti-3-Phosphatase Adapter Protein antibodyAnti-MTMR12 antibodyAnti-KIAA1682 antibodyAnti-PIP3AP antibody |
Information sourced from Uniprot.org