| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTHFD2 |
| Gene ID: | 10797 |
| Uniprot ID: | MTDC_HUMAN |
| Immunogen Region: | 40-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2). |
| Immunogen Sequence: | ISGRKLAQQIKQEVRQEVEE WVASGNKRPHLSVILVGENP ASHSYVLNKTRAAAVVGINS ETIMKPASISEEELLNLINK LNNDDNVDGLLVQLPLPEHI DERRICNAVSPDKDVDGFHV INVGRMCLDQYSMLPATPWG VWEIIKRTGIPTLGKNVVVA GRSKNVGMPIAMLLHTDGAH ERPGGDATVTISHRYTPKEQ LKKHTILADIV |
| Function | Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency. |
| Protein Name | Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase antibodyAnti-MTHFD2 antibodyAnti-NMDMC antibody |
Information sourced from Uniprot.org