Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Methionine-R-sulfoxide reductase B1 is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MSRB1 |
Gene ID: | 51734 |
Uniprot ID: | MSRB1_HUMAN |
Specificity: | This antibody detects endogenous levels of SEPX1 at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human SEPX1 |
Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages. |
Protein Name | Methionine-R-Sulfoxide Reductase B1Msrb1Selenoprotein XSelx |
Database Links | Reactome: R-HSA-5676934 |
Cellular Localisation | CytoplasmNucleusCytoskeleton |
Alternative Antibody Names | Anti-Methionine-R-Sulfoxide Reductase B1 antibodyAnti-Msrb1 antibodyAnti-Selenoprotein X antibodyAnti-Selx antibodyAnti-MSRB1 antibodyAnti-SEPX1 antibodyAnti-HSPC270 antibody |
Information sourced from Uniprot.org