Anti-MRC1 antibody (610-1456) (STJ111269)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MRC1 (610-1456) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRC1 |
| Gene ID | 4360 |
| Uniprot ID | MRC1_HUMAN |
| Immunogen Region | 610-1456 |
| Immunogen Sequence | GLWDVLKCDEKAKFVCKHWA EGVTHPPKPTTTPEPKCPED WGASSRTSLCFKLYAKGKHE KKTWFESRDFCRALGGDLAS INNKEEQQTIWRLITASGSY HKLFWLGLTYGSPSEGFTWS DGSPVSYENWAYGEPNNYQN VEYCGELKGDPTMSWNDINC EHLNNWICQIQKGQTPKPEP TPAPQDNPPVTEDGWVIYKD YQYYFSKEKETMDNARAFCK RNFGDLVSIQSESEKKFLW |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 610-860 of human Mannose Receptor/CD206 (NP_002429.1). |
Additional Info
| Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. |
| Protein Name | Macrophage Mannose Receptor 1MmrC-Type Lectin Domain Family 13 Member DC-Type Lectin Domain Family 13 Member D-LikeHuman Mannose ReceptorHmrMacrophage Mannose Receptor 1-Like Protein 1Cd Antigen Cd206 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-9637628 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Macrophage Mannose Receptor 1 antibodyAnti-Mmr antibodyAnti-C-Type Lectin Domain Family 13 Member D antibodyAnti-C-Type Lectin Domain Family 13 Member D-Like antibodyAnti-Human Mannose Receptor antibodyAnti-Hmr antibodyAnti-Macrophage Mannose Receptor 1-Like Protein 1 antibodyAnti-Cd Antigen Cd206 antibodyAnti-MRC1 antibodyAnti-CLEC13D antibodyAnti-CLEC13DL antibodyAnti-MRC1L1 antibody |
Information sourced from Uniprot.org