| Short Description : | Rabbit polyclonal anti-Protein Mpv17 (45-95 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MPV17 |
| Gene ID: | 4358 |
| Uniprot ID: | MPV17_HUMAN |
| Immunogen: | Synthesized peptide derived from the human MPV17 at the amino acid range 45-95 |
| Immunogen Region: | 45-95 aa |
| Specificity: | This antibody detects endogenous levels of MPV17 at Human/Mouse/Rat |
| Function | Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance. May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation. |
| Protein Name | Mitochondrial Inner Membrane Protein Mpv17Protein Mpv17 |
| Database Links | Reactome: R-HSA-9033241 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Inner Membrane Protein Mpv17 antibodyAnti-Protein Mpv17 antibodyAnti-MPV17 antibody |
Information sourced from Uniprot.org
