| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MP100/NPEPPS (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 110kDa band observed in Human Brain (Cerebral Cortex) lysates (calculated MW of 98.5kDa according to NP_006301.2). Recommended concentration: 0.2-0.5µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NPEPPS |
| Gene ID: | 9520 |
| Uniprot ID: | PSA_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_006301.2 |
| Immunogen Sequence: | KRDAESIHQYLLQRK |
| Function | Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. |
| Protein Name | Puromycin-Sensitive AminopeptidasePsaCytosol Alanyl AminopeptidaseAap-S |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Puromycin-Sensitive Aminopeptidase antibodyAnti-Psa antibodyAnti-Cytosol Alanyl Aminopeptidase antibodyAnti-Aap-S antibodyAnti-NPEPPS antibodyAnti-PSA antibody |
Information sourced from Uniprot.org