• Anti-Monocyte Antigen antibody [IPO-M6] (STJ16100825)

Anti-Monocyte Antigen antibody [IPO-M6] (STJ16100825)

SKU:
STJ16100825

£264.50 - £1,251.50
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Host: Mouse
Applications: FC/IHC/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Monocyte antigen is suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: IPO-M6
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow cytometry (0.5-1.0 µg/million cells in 0.1 ml). Immunohistology (1-2 µg/ml for 30 min at RT). Immunoprecipitation (1-2 µg/million cells in 1ml anti mouse coated Sepharose-4B suspension).
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Immunogen: A BALB/c mouse was immunized with human cell line HL-60. Fusion partner: P3-X63-Ag8.653.
Background IPO-M6 reacts with human leukemia cell line HL-60 and immuno-precipitates two proteins with MW of 48 and 52 kDa. IPO-M6 does not stain B cell lines Daudy, PHS, Namalwa, RPMI-1788 and T-cell lines CCRF-HSB2, Jurkat and Molt-4. IPO-M6 can be applied for staining of monocytes and up to 10 % of lymphocytes from peripheral blood of healthy donors. Blast cells of patients with AMMonL (M5 following FAB classification) , AMMonL (M4) and hairy cells leukemia are IPO-M6 positive. The antigen, defined by IPO-M6, is particularly expressed on blood cells from patients with infectious mononucleosis and CLL. Histiocytes and macrophages are also positive. Malignant cells from patients with AML (M1 and M2) , T-ALL, B ALL are IPO-M6 negative.

Information sourced from Uniprot.org

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