• Western blot analysis of extracts of various cell lines, using MNX1/MNX1/HB9/HLXB9 Rabbit monoclonal antibody (STJ11103083) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-MNX1/HB9/HLXB9 antibody (250-350) [S3MR] (STJ11103083)

SKU:
STJ11103083

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-MNX1/HB9/HLXB9 (250-350) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S3MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MNX1
Gene ID: 3110
Uniprot ID: MNX1_HUMAN
Immunogen Region: 250-350
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MNX1/HB9/HLXB9 (P50219).
Immunogen Sequence: SQQLLELEHQFKLNKYLSRP KRFEVATSLMLTETQVKIWF QNRRMKWKRSKKAKEQAAQE AEKQKGGGGGAGKGGAEEPG AEELLGPPAPGDKGSGRRLR D
Tissue Specificity Expressed in lymphoid and pancreatic tissues.
Function Transcription factor. Recognizes and binds to the regulatory elements of target genes, such as visual system homeobox CHX10, negatively modulating transcription. Plays a role in establishing motor neuron identity, in concert with LIM domain transcription factor LMO4. Involved in negatively modulating transcription of interneuron genes in motor neurons, acting, at least in part, by blocking regulatory sequence interactions of the ISL1-LHX3 complex. Involved in pancreas development and function.may play a role in pancreatic cell fate specification.
Protein Name Motor Neuron And Pancreas Homeobox Protein 1
Homeobox Protein Hb9
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Motor Neuron And Pancreas Homeobox Protein 1 antibody
Anti-Homeobox Protein Hb9 antibody
Anti-MNX1 antibody
Anti-HLXB9 antibody

Information sourced from Uniprot.org

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