Anti-MNX1/HB9/HLXB9 antibody (250-350) [S3MR] (STJ11103083)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MNX1/HB9/HLXB9 (250-350) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MNX1 |
| Gene ID | 3110 |
| Uniprot ID | MNX1_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | SQQLLELEHQFKLNKYLSRP KRFEVATSLMLTETQVKIWF QNRRMKWKRSKKAKEQAAQE AEKQKGGGGGAGKGGAEEPG AEELLGPPAPGDKGSGRRLR D |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MNX1/HB9/HLXB9 (P50219). |
Additional Info
| Tissue Specificity | Expressed in lymphoid and pancreatic tissues. |
| Function | Transcription factor. Recognizes and binds to the regulatory elements of target genes, such as visual system homeobox CHX10, negatively modulating transcription. Plays a role in establishing motor neuron identity, in concert with LIM domain transcription factor LMO4. Involved in negatively modulating transcription of interneuron genes in motor neurons, acting, at least in part, by blocking regulatory sequence interactions of the ISL1-LHX3 complex. Involved in pancreas development and function.may play a role in pancreatic cell fate specification. |
| Protein Name | Motor Neuron And Pancreas Homeobox Protein 1Homeobox Protein Hb9 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Motor Neuron And Pancreas Homeobox Protein 1 antibodyAnti-Homeobox Protein Hb9 antibodyAnti-MNX1 antibodyAnti-HLXB9 antibody |
Information sourced from Uniprot.org