| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP25 |
| Gene ID: | 64386 |
| Uniprot ID: | MMP25_HUMAN |
| Immunogen Region: | 321-539 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 321-539 of human MMP25 (NP_071913.1). |
| Immunogen Sequence: | FDAIANIRGETFFFKGPWFW RLQPSGQLVSPRPARLHRFW EGLPAQVRVVQAAYARHRDG RILLFSGPQFWVFQDRQLEG GARPLTELGLPPGEEVDAVF SWPQNGKTYLVRGRQYWRYD EAAARPDPGYPRDLSLWEGA PPSPDDVTVSNAGDTYFFKG AHYWRFPKNSIKTEPDAPQP MGPNWLDCPAPSSGPRAPRP PKATPVSETCDCQCELNQA |
| Tissue Specificity | Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-25Mmp-25LeukolysinMembrane-Type Matrix Metalloproteinase 6Mt-Mmp 6Mtmmp6Membrane-Type-6 Matrix MetalloproteinaseMt6-MmpMt6mmp |
| Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorExtracellular SideSecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-25 antibodyAnti-Mmp-25 antibodyAnti-Leukolysin antibodyAnti-Membrane-Type Matrix Metalloproteinase 6 antibodyAnti-Mt-Mmp 6 antibodyAnti-Mtmmp6 antibodyAnti-Membrane-Type-6 Matrix Metalloproteinase antibodyAnti-Mt6-Mmp antibodyAnti-Mt6mmp antibodyAnti-MMP25 antibodyAnti-MMP20 antibodyAnti-MMPL1 antibodyAnti-MT6MMP antibody |
Information sourced from Uniprot.org