Anti-MMP1 antibody [6A5] (STJ98247)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MMP-1 expressed in E. Coli.
STJ98247
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General Information

Short DescriptionMouse monoclonal anti-Interstitial collagenase for use in WB, IHC, IF, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/FC/ELISA
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID6A5
IsotypeIgG1
ConjugationUnconjugated
PurificationAffinity purification
Dilution RangeWB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000
FormulationLiquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMMP1
Gene ID4312
Uniprot IDMMP1_HUMAN
ImmunogenPurified recombinant fragment of human MMP-1 expressed in E. Coli.
SpecificityMMP-1 Monoclonal Antibody detects endogenous levels of MMP-1 protein.

Additional Info

Function Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
Protein Name Interstitial Collagenase
Fibroblast Collagenase
Matrix Metalloproteinase-1
Mmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Reactome: R-HSA-210991
Reactome: R-HSA-381426
Reactome: R-HSA-6785807
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Interstitial Collagenase antibody
Anti-Fibroblast Collagenase antibody
Anti-Matrix Metalloproteinase-1 antibody
Anti-Mmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase antibody
Anti-MMP1 antibody
Anti-CLG antibody

Information sourced from Uniprot.org

Citations

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