| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MLC1 (179-193) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 70kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 41.1kDa according to NP_055981.1). The observed molecular weight corresponds to earlier findings in l |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MLC1 |
| Gene ID: | 23209 |
| Uniprot ID: | MLC1_HUMAN |
| Immunogen Region: | 179-193 |
| Accession Number: | NP_055981.1 |
| Specificity: | Reported variants represent identical protein: NP_631941.1, NP_055981.1. |
| Immunogen Sequence: | SDSANILDEVPFPAR |
| Function | Transmembrane protein mainly expressed in brain atrocytes that may play a role in transport across the blood-brain and brain-cerebrospinal fluid barriers. Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. May function as regulatory protein of membrane protein complexes such as ion channels (Probable). |
| Protein Name | Membrane Protein Mlc1Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmPerinuclear RegionEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Membrane Protein Mlc1 antibodyAnti-Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 antibodyAnti-MLC1 antibodyAnti-KIAA0027 antibodyAnti-WKL1 antibody |
Information sourced from Uniprot.org