• Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MKKS antibody (166-216 aa) (STJ193644)

SKU:
STJ193644

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Molecular chaperone MKKS (166-216 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MKKS
Gene ID: 8195
Uniprot ID: MKKS_HUMAN
Immunogen Region: 166-216 aa
Specificity: This antibody detects endogenous levels of MKKS at Human/Mouse
Immunogen: Synthesized peptide derived from the human MKKS at the amino acid range 166-216
Function Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
Protein Name Molecular Chaperone Mkks
Bardet-Biedl Syndrome 6 Protein
Mckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin
Database Links Reactome: R-HSA-5620922
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cytosol
Nucleus
The Majority Of The Protein Resides Within The Pericentriolar Material (Pcm)
A Proteinaceous Tube Surrounding Centrioles
During Interphase
The Protein Is Confined To The Lateral Surfaces Of The Pcm But During Mitosis It Relocalizes Throughout The Pcm And Is Found At The Intercellular Bridge
The Mkss Protein Is Highly Mobile And Rapidly Shuttles Between The Cytosol And Centrosome
Alternative Antibody Names Anti-Molecular Chaperone Mkks antibody
Anti-Bardet-Biedl Syndrome 6 Protein antibody
Anti-Mckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin antibody
Anti-MKKS antibody
Anti-BBS6 antibody

Information sourced from Uniprot.org

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