Anti-MKKS antibody (166-216 aa) (STJ193644)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MKKS at the amino acid range 166-216
General Information
| Short Description | Rabbit polyclonal anti-Molecular chaperone MKKS (166-216 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MKKS |
| Gene ID | 8195 |
| Uniprot ID | MKKS_HUMAN |
| Immunogen | Synthesized peptide derived from the human MKKS at the amino acid range 166-216 |
| Immunogen Region | 166-216 aa |
| Specificity | This antibody detects endogenous levels of MKKS at Human/Mouse |
Additional Info
| Function | Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. |
| Protein Name | Molecular Chaperone MkksBardet-Biedl Syndrome 6 ProteinMckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin |
| Database Links | Reactome: R-HSA-5620922 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCytosolNucleusThe Majority Of The Protein Resides Within The Pericentriolar Material (Pcm)A Proteinaceous Tube Surrounding CentriolesDuring InterphaseThe Protein Is Confined To The Lateral Surfaces Of The Pcm But During Mitosis It Relocalizes Throughout The Pcm And Is Found At The Intercellular BridgeThe Mkss Protein Is Highly Mobile And Rapidly Shuttles Between The Cytosol And Centrosome |
| Alternative Antibody Names | Anti-Molecular Chaperone Mkks antibodyAnti-Bardet-Biedl Syndrome 6 Protein antibodyAnti-Mckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin antibodyAnti-MKKS antibodyAnti-BBS6 antibody |
Information sourced from Uniprot.org