Anti-MITD1 antibody (1-249) (STJ11100491)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MITD1 (1-249) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MITD1 |
| Gene ID | 129531 |
| Uniprot ID | MITD1_HUMAN |
| Immunogen Region | 1-249 |
| Immunogen Sequence | MAKSGLRQDPQSTAAATVLK RAVELDSESRYPQALVCYQE GIDLLLQVLKGTKDNTKRCN LREKISKYMDRAENIKKYLD QEKEDGKYHKQIKIEENATG FSYESLFREYLNETVTEVWI EDPYIRHTHQLYNFLRFCEM LIKRPCKVKTIHLLTSLDEG IEQVQQSRGLQEIEESLRSH GVLLEVQYSSSIHDREIRFN NGWMIKIGRGLDYFKKPQSR FSLGYCDFDLRPCHETTVD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human MITD1 (NP_620153.1). |
Additional Info
| Function | Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. |
| Protein Name | Mit Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinCytoplasmic SideMidbodyMembraneDuring CytokinesisRecruited To The Midbody Via Interaction With Chmp1aInteracts With Membranes Enriched In Phosphoinositides |
| Alternative Antibody Names | Anti-Mit Domain-Containing Protein 1 antibodyAnti-MITD1 antibody |
Information sourced from Uniprot.org