• Western blot analysis of lysates from mouse brain, using mGluR2/3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR2/3 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-mGluR-2/3 antibody (823-872 aa) (STJ94108)

SKU:
STJ94108

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Metabotropic glutamate receptor 2 and Metabotropic glutamate receptor 3 (823-872 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM2
GRM3
Gene ID: 2912
2913
Uniprot ID: GRM2_HUMAN
GRM3_HUMAN
Immunogen Region: 823-872 aa
Specificity: mGluR-2/3 Polyclonal Antibody detects endogenous levels of mGluR-2/3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human mGluR2/3 at the amino acid range 823-872
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Protein Name Metabotropic Glutamate Receptor 2
Mglur2
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Junction
Synapse
Cell Projection
Dendrite
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 2 antibody
Anti-Mglur2 antibody
Anti-GRM2 antibody
Anti-GPRC1B antibody
Anti-MGLUR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance