| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MELTF |
| Gene ID: | 4241 |
| Uniprot ID: | TRFM_HUMAN |
| Immunogen Region: | 20-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1). |
| Immunogen Sequence: | GMEVRWCATSDPEQHKCGNM SEAFREAGIQPSLLCVRGTS ADHCVQLIAAQEADAITLDG GAIYEAGKEHGLKPVVGEVY DQEVGTSYYAVAVVRRSSHV TIDTLKGVKSCHTGINRTVG WNVPVGYLVESGRLSVMGCD VLKAVSDYFGGSCVPGAGET SYSESLCRLCRGDSSGEGVC D |
| Tissue Specificity | Found predominantly in human melanomas and in certain fetal tissues.also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts. |
| Function | Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. |
| Protein Name | Melanotransferrin Melanoma-Associated Antigen P97 Cd Antigen Cd228 |
| Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-Melanotransferrin antibody Anti-Melanoma-Associated Antigen P97 antibody Anti-Cd Antigen Cd228 antibody Anti-MELTF antibody Anti-MAP97 antibody Anti-MFI2 antibody |
Information sourced from Uniprot.org