• Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MER34 antibody (STJ193569)

SKU:
STJ193569
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Short Description: Rabbit polyclonal primary antibody against MER34.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using a specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-2000
Specificity: This antibody detects endogenous levels of MER34 at Human
Uniprot ID: MER34_HUMAN
Gene ID: 100288413
Gene Symbol: ERVMER34-1
Immunogen: Synthesized peptide derived from human MER34
Tissue Specificity Expressed at high level in the placenta and stem cells (at protein level). Also expressed in the kidney but at a lower level. Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level).
Post Translational Modifications N-glycosylated. Endogenous retroviral envelope protein HEMO: Cleaved by some metalloproteinase at 432-Gln-Arg-433 (mainly) or 433-Arg-Gln-434, leading to release the secreted form (Endogenous retroviral envelope protein HEMO, secreted form) in the extracellular medium.
Function Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.
Cellular Localisation Endogenous Retroviral Envelope Protein Hemo: Cell Membrane
Single-Pass Type I Membrane Protein
This Uncleaved Form Present At The Cell Surface Represents The Major Form
Endogenous Retroviral Envelope Protein Hemo
Secreted Form: Secreted
This Secreted Form
Which Is Released In The Extracellular Medium Following Cleavage
Constitutes A Minor Form
Protein Name Endogenous Retroviral Envelope Protein Hemo
Endogenous Retrovirus Group Mer34 Member 1 Env Polyprotein
Herv-Mer_4q12 Provirus Ancestral Env Polyprotein
Human Endogenous Mer34
Medium-Reiteration-Frequency-Family-34 Open Reading Frame
Human Endogenous Mer34 Orf
Hemo Cleaved Into - Endogenous Retroviral Envelope Protein Hemo - Secreted Form
Endogenous Retroviral Envelope Protein Hemo - 48 Kda Form
Alternative Names Anti-Endogenous Retroviral Envelope Protein Hemo antibody
Anti-Endogenous Retrovirus Group Mer34 Member 1 Env Polyprotein antibody
Anti-Herv-Mer_4q12 Provirus Ancestral Env Polyprotein antibody
Anti-Human Endogenous Mer34 antibody
Anti-Medium-Reiteration-Frequency-Family-34 Open Reading Frame antibody
Anti-Human Endogenous Mer34 Orf antibody
Anti-Hemo Cleaved Into - Endogenous Retroviral Envelope Protein Hemo - Secreted Form antibody
Anti-Endogenous Retroviral Envelope Protein Hemo - 48 Kda Form antibody
Anti-ERVMER34-1 antibody
Anti-HEMO antibody
Anti-LP9056 antibody

Information sourced from Uniprot.org

6 months standard