| Tissue Specificity | Expressed specifically in fetal ovary and postnatal and adult testes (at protein level). In adult testis expressed in spermatocytes, beginning in preleptotene and extending through most stages of meiotic prophase I, including leptotene, zygotene, and pachytene. |
| Function | Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. |
| Protein Name | Meiosis-Specific Coiled-Coil Domain-Containing Protein MeiocMeiosis-Specific With Coiled-Coil Domain Protein |
| Cellular Localisation | CytoplasmNucleusAt Late Pachytene A Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Meiosis-Specific Coiled-Coil Domain-Containing Protein Meioc antibodyAnti-Meiosis-Specific With Coiled-Coil Domain Protein antibodyAnti-Meioc antibodyAnti-Gm1564 antibody |
Information sourced from Uniprot.org
