Post Translational Modifications | Constitutively sumoylated. |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 7Hmed7Activator-Recruited Cofactor 34 Kda ComponentArc34Cofactor Required For Sp1 Transcriptional Activation Subunit 9Crsp Complex Subunit 9Mediator Complex Subunit 7Rna Polymerase Transcriptional Regulation Mediator Subunit 7 HomologTranscriptional Coactivator Crsp33 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 7 antibodyAnti-Hmed7 antibodyAnti-Activator-Recruited Cofactor 34 Kda Component antibodyAnti-Arc34 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 9 antibodyAnti-Crsp Complex Subunit 9 antibodyAnti-Mediator Complex Subunit 7 antibodyAnti-Rna Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog antibodyAnti-Transcriptional Coactivator Crsp33 antibodyAnti-MED7 antibodyAnti-ARC34 antibodyAnti-CRSP9 antibody |
Information sourced from Uniprot.org