Anti-MED7 antibody (1-233) (STJ118528)

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STJ118528
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Short Description :Rabbit polyclonal MED7 (1-233) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MED7
Gene ID:9443
Uniprot ID:MED7_HUMAN
Immunogen Region:1-233
Immunogen Sequence:MGEPQQVSALPPPPMQYIKE YTDENIQEGLAPKPPPPIKD SYMMFGNQFQCDDLIIRPLE SQGIERLHPMQFDHKKELRK LNMSILINFLDLLDILIRSP GSIKREEKLEDLKLLFVHVH HLINEYRPHQARETLRVMME VQKRQRLETAERFQKHLERV IEMIQNCLASLPDDLPHSEA GMRVKTEPMDADDSNNCTGQ NEHQRENSGHRRDQIIEKDA ALCVLIDEMNERP
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human MED7 (NP_004261.1).
Post Translational Modifications Constitutively sumoylated.
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Name Mediator Of Rna Polymerase Ii Transcription Subunit 7
Hmed7
Activator-Recruited Cofactor 34 Kda Component
Arc34
Cofactor Required For Sp1 Transcriptional Activation Subunit 9
Crsp Complex Subunit 9
Mediator Complex Subunit 7
Rna Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog
Transcriptional Coactivator Crsp33
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-212436
Reactome: R-HSA-381340
Reactome: R-HSA-9833110
Reactome: R-HSA-9841922
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 7 antibody
Anti-Hmed7 antibody
Anti-Activator-Recruited Cofactor 34 Kda Component antibody
Anti-Arc34 antibody
Anti-Cofactor Required For Sp1 Transcriptional Activation Subunit 9 antibody
Anti-Crsp Complex Subunit 9 antibody
Anti-Mediator Complex Subunit 7 antibody
Anti-Rna Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog antibody
Anti-Transcriptional Coactivator Crsp33 antibody
Anti-MED7 antibody
Anti-ARC34 antibody
Anti-CRSP9 antibody

Information sourced from Uniprot.org