Anti-MED28 antibody (20-100 aa) (STJ190947)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 20-100
General Information
| Short Description | Rabbit polyclonal anti-Mediator of RNA polymerase II transcription subunit 28 (20-100 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED28 |
| Gene ID | 80306 |
| Uniprot ID | MED28_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 20-100 |
| Immunogen Region | 20-100 aa |
| Specificity | MED28 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 28Endothelial-Derived Protein 1Mediator Complex Subunit 28Merlin And Grb2-Interacting Cytoskeletal ProteinMagicinTumor Angiogenesis Marker Eg-1 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | NucleusCytoplasmMembranePeripheral Membrane ProteinIt Is Cytoplasmic And Mainly Membrane-Associated |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 28 antibodyAnti-Endothelial-Derived Protein 1 antibodyAnti-Mediator Complex Subunit 28 antibodyAnti-Merlin And Grb2-Interacting Cytoskeletal Protein antibodyAnti-Magicin antibodyAnti-Tumor Angiogenesis Marker Eg-1 antibodyAnti-MED28 antibodyAnti-EG1 antibodyAnti-FKSG20 antibody |
Information sourced from Uniprot.org