Anti-MED26 antibody (500-574) (STJ11103350)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MED26 (500-574) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED26 |
| Gene ID | 9441 |
| Uniprot ID | MED26_HUMAN |
| Immunogen Region | 500-574 |
| Immunogen Sequence | SGAQTPGAHHFMSEYLKQEE STRQGARQLHVLVPQSPPTD LPGLTREVTQDDLDRIQASQ WPGVNGCQDTQGNWY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 500-574 of human MED26 (NP_004822.2). |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 26Activator-Recruited Cofactor 70 Kda ComponentArc70Cofactor Required For Sp1 Transcriptional Activation Subunit 7Crsp Complex Subunit 7Mediator Complex Subunit 26Transcriptional Coactivator Crsp70 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 26 antibodyAnti-Activator-Recruited Cofactor 70 Kda Component antibodyAnti-Arc70 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 7 antibodyAnti-Crsp Complex Subunit 7 antibodyAnti-Mediator Complex Subunit 26 antibodyAnti-Transcriptional Coactivator Crsp70 antibodyAnti-MED26 antibodyAnti-ARC70 antibodyAnti-CRSP7 antibody |
Information sourced from Uniprot.org