| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MC2R |
| Gene ID: | 4158 |
| Uniprot ID: | ACTHR_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MC2R (NP_000520.1) |
| Immunogen Sequence: | MKHIINSYENINNTARNNSD CPRVVLPEEIFFTISIVGVL ENLIVLLAVFKNKNLQAPMY FFICSLAISDMLGSLYKILE NILIILRNMGYLKPRGSFET |
| Tissue Specificity | Melanocytes and corticoadrenal tissue. |
| Function | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). |
| Protein Name | Adrenocorticotropic Hormone ReceptorActh ReceptorActh-RAdrenocorticotropin ReceptorMelanocortin Receptor 2Mc2-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-5579031 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adrenocorticotropic Hormone Receptor antibodyAnti-Acth Receptor antibodyAnti-Acth-R antibodyAnti-Adrenocorticotropin Receptor antibodyAnti-Melanocortin Receptor 2 antibodyAnti-Mc2-R antibodyAnti-MC2R antibodyAnti-ACTHR antibody |
Information sourced from Uniprot.org
