| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MB |
| Gene ID: |
4151 |
| Uniprot ID: |
MYG_HUMAN |
| Immunogen Region: |
1-154 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human Myoglobin (NP_005359.1). |
| Immunogen Sequence: |
MGLSDGEWQLVLNVWGKVEA DIPGHGQEVLIRLFKGHPET LEKFDKFKHLKSEDEMKASE DLKKHGATVLTALGGILKKK GHHEAEIKPLAQSHATKHKI PVKYLEFISECIIQVLQSKH PGDFGADAQGAMNKALELFR KDMASNYKELGFQG |
| Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. |
| Protein Name | MyoglobinNitrite Reductase MbPseudoperoxidase Mb |
| Database Links | Reactome: R-HSA-8981607 |
| Cellular Localisation | CytoplasmSarcoplasm |
| Alternative Antibody Names | Anti-Myoglobin antibodyAnti-Nitrite Reductase Mb antibodyAnti-Pseudoperoxidase Mb antibodyAnti-MB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
