| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Megakaryocyte-associated tyrosine-protein kinase (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MATK |
| Gene ID: | 4145 |
| Uniprot ID: | MATK_HUMAN |
| Immunogen Region: | Internal |
| Specificity: | Lsk Polyclonal Antibody detects endogenous levels of Lsk protein. |
| Immunogen: | Synthesized peptide derived from the Internal region of human Lsk. |
| Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. |
| Protein Name | Megakaryocyte-Associated Tyrosine-Protein KinaseCsk Homologous KinaseChkHematopoietic Consensus Tyrosine-Lacking KinaseProtein Kinase HylTyrosine-Protein Kinase Ctk |
| Database Links | Reactome: R-HSA-8863795 |
| Cellular Localisation | CytoplasmMembraneIn Platelets90% Of Matk Localizes To The Membrane FractionAnd Translocates To The Cytoskeleton Upon Thrombin Stimulation |
| Alternative Antibody Names | Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibodyAnti-Csk Homologous Kinase antibodyAnti-Chk antibodyAnti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibodyAnti-Protein Kinase Hyl antibodyAnti-Tyrosine-Protein Kinase Ctk antibodyAnti-MATK antibodyAnti-CTK antibodyAnti-HYL antibody |
Information sourced from Uniprot.org