• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA, pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200 (4°C overnight. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-MATK antibody (Internal) (STJ93960)

SKU:
STJ93960

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Megakaryocyte-associated tyrosine-protein kinase (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MATK
Gene ID: 4145
Uniprot ID: MATK_HUMAN
Immunogen Region: Internal
Specificity: Lsk Polyclonal Antibody detects endogenous levels of Lsk protein.
Immunogen: Synthesized peptide derived from the Internal region of human Lsk.
Function Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Protein Name Megakaryocyte-Associated Tyrosine-Protein Kinase
Csk Homologous Kinase
Chk
Hematopoietic Consensus Tyrosine-Lacking Kinase
Protein Kinase Hyl
Tyrosine-Protein Kinase Ctk
Database Links Reactome: R-HSA-8863795
Cellular Localisation Cytoplasm
Membrane
In Platelets
90% Of Matk Localizes To The Membrane Fraction
And Translocates To The Cytoskeleton Upon Thrombin Stimulation
Alternative Antibody Names Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibody
Anti-Csk Homologous Kinase antibody
Anti-Chk antibody
Anti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibody
Anti-Protein Kinase Hyl antibody
Anti-Tyrosine-Protein Kinase Ctk antibody
Anti-MATK antibody
Anti-CTK antibody
Anti-HYL antibody

Information sourced from Uniprot.org

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