• Immunofluorescence analysis of mouse lung cells using MARCO Rabbit polyclonal antibody (STJ112088) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of rat lung cells using MARCO Rabbit polyclonal antibody (STJ112088) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using MARCO antibody (STJ112088) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-MARCO antibody (421-520) (STJ112088)

SKU:
STJ112088

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MARCO
Gene ID: 8685
Uniprot ID: MARCO_HUMAN
Immunogen Region: 421-520
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 421-520 of human MARCO (NP_006761.1).
Immunogen Sequence: SVSVRIVGSSNRGRAEVYYS GTWGTICDDEWQNSDAIVFC RMLGYSKGRALYKVGAGTGQ IWLDNVQCRGTESTLWSCTK NSWGHHDCSHEEDAGVECSV
Tissue Specificity Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen.
Post Translational Modifications N-glycosylated.
Function Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2.
Protein Name Macrophage Receptor Marco
Macrophage Receptor With Collagenous Structure
Scavenger Receptor Class A Member 2
Database Links Reactome: R-HSA-3000480
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Macrophage Receptor Marco antibody
Anti-Macrophage Receptor With Collagenous Structure antibody
Anti-Scavenger Receptor Class A Member 2 antibody
Anti-MARCO antibody
Anti-SCARA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance