| Short Description : | Rabbit polyclonal MARCH9 (277-346) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MARCHF9 |
| Gene ID: | 92979 |
| Uniprot ID: | MARH9_HUMAN |
| Immunogen Region: | 277-346 |
| Immunogen Sequence: | GTAGKSGPRNSRTGPTSGAT SRPPAAQRMRTLLPQRCGYT ILHLLGQLRPPDARSSSHSG REVVMRVTTV |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2). |
| Tissue Specificity | Ubiquitously expressed. |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf9Membrane-Associated Ring Finger Protein 9Membrane-Associated Ring-Ch Protein IxMarch-IxRing Finger Protein 179Ring-Type E3 Ubiquitin Transferase Marchf9 |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome Membrane |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf9 antibodyAnti-Membrane-Associated Ring Finger Protein 9 antibodyAnti-Membrane-Associated Ring-Ch Protein Ix antibodyAnti-March-Ix antibodyAnti-Ring Finger Protein 179 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf9 antibodyAnti-MARCHF9 antibodyAnti-MARCH9 antibodyAnti-RNF179 antibody |
Information sourced from Uniprot.org
