• Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 using MEK-5 Polyclonal Antibody. Secondary antibody (STJ99666) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).
  • Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using MEK-5 Polyclonal Antibody.

Anti-MAP2K5 antibody (STJ197347)

SKU:
STJ197347

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dual specificity mitogen-activated protein kinase kinase 5 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range: WB 1:1000-2000
IHC 1:200-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAP2K5
Gene ID: 5607
Uniprot ID: MP2K5_HUMAN
Specificity: The antibody detects endogenous MEK-5 protein.
Immunogen: Recombinant Protein of MEK-5
Post Translational Modifications Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. (Microbial infection) Yersinia YopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway.
Function Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Protein Name Dual Specificity Mitogen-Activated Protein Kinase Kinase 5
Map Kinase Kinase 5
Mapkk 5
Mapk/Erk Kinase 5
Mek 5
Database Links Reactome: R-HSA-198765
Alternative Antibody Names Anti-Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 antibody
Anti-Map Kinase Kinase 5 antibody
Anti-Mapkk 5 antibody
Anti-Mapk/Erk Kinase 5 antibody
Anti-Mek 5 antibody
Anti-MAP2K5 antibody
Anti-MEK5 antibody
Anti-MKK5 antibody
Anti-PRKMK5 antibody

Information sourced from Uniprot.org

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