| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAN2B1 (640-850) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAN2B1 |
| Gene ID: |
4125 |
| Uniprot ID: |
MA2B1_HUMAN |
| Immunogen Region: |
640-850 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 640-850 of human MAN2B1 (NP_000519.2). |
| Immunogen Sequence: |
TFFWYNASIGDNESDQASGA YIFRPNQQKPLPVSRWAQIH LVKTPLVQEVHQNFSAWCSQ VVRLYPGQRHLELEWSVGPI PVGDTWGKEVISRFDTPLET KGRFYTDSNGREILERRRDY RPTWKLNQTEPVAGNYYPVN TRIYITDGNMQLTVLTDRSQ GGSSLRDGSLELMVHRRLLK DDGRGVSEPLMENGSGAWVR GRHLVLLDTAQ |
| Post Translational Modifications | First processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). The 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Heavily glycosylated. |
| Function | Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages. |
| Protein Name | Lysosomal Alpha-MannosidaseLamanLysosomal Acid Alpha-MannosidaseMannosidase Alpha Class 2b Member 1Mannosidase Alpha-B Cleaved Into - Lysosomal Alpha-Mannosidase A Peptide - Lysosomal Alpha-Mannosidase B Peptide - Lysosomal Alpha-Mannosidase C Peptide - Lysosomal Alpha-Mannosidase D Peptide - Lysosomal Alpha-Mannosidase E Peptide |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8853383 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Alpha-Mannosidase antibodyAnti-Laman antibodyAnti-Lysosomal Acid Alpha-Mannosidase antibodyAnti-Mannosidase Alpha Class 2b Member 1 antibodyAnti-Mannosidase Alpha-B Cleaved Into - Lysosomal Alpha-Mannosidase A Peptide - Lysosomal Alpha-Mannosidase B Peptide - Lysosomal Alpha-Mannosidase C Peptide - Lysosomal Alpha-Mannosidase D Peptide - Lysosomal Alpha-Mannosidase E Peptide antibodyAnti-MAN2B1 antibodyAnti-LAMAN antibodyAnti-MANB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
