| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MAN2A1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx. 150kDa band observed in Human Placenta lysates (calculated MW of 131kDa according to NP_002363.2). In transfected HEK293 transiently expressing MAN2A1 a band of approx. 98kDa i |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MAN2A1 |
| Gene ID: | 4124 |
| Uniprot ID: | MA2A1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002363.2 |
| Immunogen Sequence: | KISSDIKSQNR |
| Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans.the final hydrolytic step in the N-glycan maturation pathway. |
| Protein Name | Alpha-Mannosidase 2Golgi Alpha-Mannosidase IiAman IiMan IiMannosidase Alpha Class 2a Member 1Mannosyl-Oligosaccharide 1 -3-1 -6-Alpha-Mannosidase |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-9694548Reactome: R-HSA-975578 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-Mannosidase 2 antibodyAnti-Golgi Alpha-Mannosidase Ii antibodyAnti-Aman Ii antibodyAnti-Man Ii antibodyAnti-Mannosidase Alpha Class 2a Member 1 antibodyAnti-Mannosyl-Oligosaccharide 1 -3-1 -6-Alpha-Mannosidase antibodyAnti-MAN2A1 antibodyAnti-MANA2 antibody |
Information sourced from Uniprot.org