| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase (100-180 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAN1B1 |
| Gene ID: |
11253 |
| Uniprot ID: |
MA1B1_HUMAN |
| Immunogen Region: |
100-180 aa |
| Specificity: |
MAN1B1 Polyclonal Antibody detects endogenous levels of MAN1B1 protein. |
| Immunogen: |
Synthesized peptide derived from MAN1B1 at the amino acid range 100-180 |
| Function | Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2). |
| Protein Name | Endoplasmic Reticulum Mannosyl-Oligosaccharide 1 -2-Alpha-MannosidaseEr Alpha-1 -2-MannosidaseEr Mannosidase 1Erman1Man9glcnac2-Specific-Processing Alpha-MannosidaseMannosidase Alpha Class 1b Member 1 |
| Database Links | Reactome: R-HSA-4793950Reactome: R-HSA-901032Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Endoplasmic Reticulum Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase antibodyAnti-Er Alpha-1 -2-Mannosidase antibodyAnti-Er Mannosidase 1 antibodyAnti-Erman1 antibodyAnti-Man9glcnac2-Specific-Processing Alpha-Mannosidase antibodyAnti-Mannosidase Alpha Class 1b Member 1 antibodyAnti-MAN1B1 antibodyAnti-UNQ747 antibodyAnti-PRO1477 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
