| Tissue Specificity | Ubiquitous. Expressed at very low levels in brain, lung and kidney. |
| Function | Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues.in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Also has oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. Could indirectly play a role in Mg(2+) transport in epithelial cells (Probable). |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1Oligosaccharyl Transferase Subunit Magt1Implantation-Associated ProteinIapMagnesium Transporter Protein 1Magt1 |
| Database Links | Reactome: R-HSA-446203Reactome: R-HSA-5223345Reactome: R-HSA-6798695Reactome: R-HSA-9694548 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic ReticulumEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1 antibodyAnti-Oligosaccharyl Transferase Subunit Magt1 antibodyAnti-Implantation-Associated Protein antibodyAnti-Iap antibodyAnti-Magnesium Transporter Protein 1 antibodyAnti-Magt1 antibodyAnti-MAGT1 antibodyAnti-IAG2 antibodyAnti-PSEC0084 antibodyAnti-UNQ628 antibodyAnti-PRO1244 antibody |
Information sourced from Uniprot.org
