| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAGT1 (60-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAGT1 |
| Gene ID: |
84061 |
| Uniprot ID: |
MAGT1_HUMAN |
| Immunogen Region: |
60-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-220 of human MAGT1 (NP_115497.4). |
| Immunogen Sequence: |
SAQRKKEMVLSEKVSQLMEW TNKRPVIRMNGDKFRRLVKA PPRNYSVIVMFTALQLHRQC VVCKQADEEFQILANSWRYS SAFTNRIFFAMVDFDEGSDV FQMLNMNSAPTFINFPAKGK PKRGDTYELQVRGFSAEQIA RWIADRTDVNIRVIRPPNYA G |
| Tissue Specificity | Ubiquitous. Expressed at very low levels in brain, lung and kidney. |
| Function | Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues.in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. May be involved in Mg(2+) transport in epithelial cells. |
| Protein Name | Magnesium Transporter Protein 1Magt1Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1Oligosaccharyl Transferase Subunit Magt1Implantation-Associated ProteinIap |
| Database Links | Reactome: R-HSA-446203Reactome: R-HSA-5223345Reactome: R-HSA-6798695Reactome: R-HSA-9694548 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic ReticulumEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Magnesium Transporter Protein 1 antibodyAnti-Magt1 antibodyAnti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Magt1 antibodyAnti-Oligosaccharyl Transferase Subunit Magt1 antibodyAnti-Implantation-Associated Protein antibodyAnti-Iap antibodyAnti-MAGT1 antibodyAnti-IAG2 antibodyAnti-PSEC0084 antibodyAnti-UNQ628 antibodyAnti-PRO1244 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
