• Western blot analysis of extracts of various cell lines, using MAD3/MXD3 Rabbit monoclonal antibody (STJ11103148) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-MAD3/MXD3 antibody (100-190) [S8MR] (STJ11103148)

SKU:
STJ11103148

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-MAD3/MXD3 (100-190) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S8MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MXD3
Gene ID: 83463
Uniprot ID: MAD3_HUMAN
Immunogen Region: 100-190
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11).
Immunogen Sequence: RRARMHIQKLEDQEQRARQL KERLRSKQQSLQRQLEQLRG LAGAAERERLRADSLDSSGL SSERSDSDQEELEVDVESLV FGGEAELLRGF
Function Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Protein Name Max Dimerization Protein 3
Max Dimerizer 3
Class C Basic Helix-Loop-Helix Protein 13
Bhlhc13
Max-Associated Protein 3
Max-Interacting Transcriptional Repressor Mad3
Myx
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Max Dimerization Protein 3 antibody
Anti-Max Dimerizer 3 antibody
Anti-Class C Basic Helix-Loop-Helix Protein 13 antibody
Anti-Bhlhc13 antibody
Anti-Max-Associated Protein 3 antibody
Anti-Max-Interacting Transcriptional Repressor Mad3 antibody
Anti-Myx antibody
Anti-MXD3 antibody
Anti-BHLHC13 antibody
Anti-MAD3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance