| Tissue Specificity | Expressed in various breast cancer cell lines. |
| Function | Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide. |
| Protein Name | Acyl-Protein Thioesterase 2Apt-2Lysophospholipase IiLpl-IiLysopla IiPalmitoyl-Protein Hydrolase |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Acyl-Protein Thioesterase 2 antibodyAnti-Apt-2 antibodyAnti-Lysophospholipase Ii antibodyAnti-Lpl-Ii antibodyAnti-Lysopla Ii antibodyAnti-Palmitoyl-Protein Hydrolase antibodyAnti-LYPLA2 antibodyAnti-APT2 antibody |
Information sourced from Uniprot.org
