| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LYPLA2 (147-231) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LYPLA2 |
| Gene ID: |
11313 |
| Uniprot ID: |
LYPA2_HUMAN |
| Immunogen Region: |
147-231 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_009191.1). |
| Immunogen Sequence: |
CWLPLHRAFPQAANGSAKDL AILQCHGELDPMVPVRFGAL TAEKLRSVVTPARVQFKTYP GVMHSSCPQEMAAVKEFLEK LLPPV |
| Tissue Specificity | Expressed in various breast cancer cell lines. |
| Function | Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide. |
| Protein Name | Acyl-Protein Thioesterase 2Apt-2Lysophospholipase IiLpl-IiLysopla IiPalmitoyl-Protein Hydrolase |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Acyl-Protein Thioesterase 2 antibodyAnti-Apt-2 antibodyAnti-Lysophospholipase Ii antibodyAnti-Lpl-Ii antibodyAnti-Lysopla Ii antibodyAnti-Palmitoyl-Protein Hydrolase antibodyAnti-LYPLA2 antibodyAnti-APT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
