| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LRRC7Uniprot ID=LRRC7_HUMAN" |
| Immunogen Region: | 730-890 |
| Immunogen Sequence: | FPQPLDSKPLLSQREAVPPG NIPQRPDRLPMSDTFTDNWT DGSHYDNTGFVAEETTAENA NSNPLLSSKSRSTSSHGRRP LIRQDRIVGVPLELEQSTHR HTPETEVPPSNPWQNWTRTP SPFEDRTAFPSKLETTPTTS PLPERKEHIKESTEIPSPFS P |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1). |
| Tissue Specificity | Brain-specific. Isoform 3 is ubiquitously expressed. |
| Function | Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 7Densin-180DensinProtein Lap1 |
| Cellular Localisation | CytoplasmPostsynaptic Density |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 7 antibodyAnti-Densin-180 antibodyAnti-Densin antibodyAnti-Protein Lap1 antibodyAnti-LRRC7 antibodyAnti-KIAA1365 antibodyAnti-LAP1 antibody |
Information sourced from Uniprot.org
