Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-LRRC7 (730-890) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LRRC7Uniprot ID=LRRC7_HUMAN" |
Immunogen Region: |
730-890 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1). |
Immunogen Sequence: |
FPQPLDSKPLLSQREAVPPG NIPQRPDRLPMSDTFTDNWT DGSHYDNTGFVAEETTAENA NSNPLLSSKSRSTSSHGRRP LIRQDRIVGVPLELEQSTHR HTPETEVPPSNPWQNWTRTP SPFEDRTAFPSKLETTPTTS PLPERKEHIKESTEIPSPFS P |
Tissue Specificity | Brain-specific. Isoform 3 is ubiquitously expressed. |
Function | Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. |
Protein Name | Leucine-Rich Repeat-Containing Protein 7Densin-180DensinProtein Lap1 |
Cellular Localisation | CytoplasmPostsynaptic Density |
Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 7 antibodyAnti-Densin-180 antibodyAnti-Densin antibodyAnti-Protein Lap1 antibodyAnti-LRRC7 antibodyAnti-KIAA1365 antibodyAnti-LAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance