Anti-LRIF1 antibody (210-260 aa) (STJ193788)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human LRIF1 at the amino acid range 210-260
General Information
| Short Description | Rabbit polyclonal anti-Ligand-dependent nuclear receptor-interacting factor 1 (210-260 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LRIF1 |
| Gene ID | 55791 |
| Uniprot ID | LRIF1_HUMAN |
| Immunogen | Synthesized peptide derived from the human LRIF1 at the amino acid range 210-260 |
| Immunogen Region | 210-260 aa |
| Specificity | This antibody detects endogenous levels of LRIF1 at Human/Mouse/Rat |
Additional Info
| Function | Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells. |
| Protein Name | Ligand-Dependent Nuclear Receptor-Interacting Factor 1Hp1-Binding Protein Enriched In Inactive X Chromosome Protein 1Hbix1Receptor-Interacting Factor 1 |
| Database Links | |
| Cellular Localisation | ChromosomeNucleus MatrixLocalizes To Barr BodyRecruited By Smchd1 |
| Alternative Antibody Names | Anti-Ligand-Dependent Nuclear Receptor-Interacting Factor 1 antibodyAnti-Hp1-Binding Protein Enriched In Inactive X Chromosome Protein 1 antibodyAnti-Hbix1 antibodyAnti-Receptor-Interacting Factor 1 antibodyAnti-LRIF1 antibodyAnti-C1orf103 antibodyAnti-RIF1 antibody |
Information sourced from Uniprot.org