| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LPCAT2 (160-544) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LPCAT2 |
| Gene ID: |
54947 |
| Uniprot ID: |
PCAT2_HUMAN |
| Immunogen Region: |
160-544 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 160-544 of human LPCAT2 (NP_060309.2). |
| Immunogen Sequence: |
LPSMVSRNENAQVPLIGRLL RAVQPVLVSRVDPDSRKNTI NEIIKRTTSGGEWPQILVFP EGTCTNRSCLITFKPGAFIP GVPVQPVLLRYPNKLDTVTW TWQGYTFIQLCMLTFCQLFT KVEVEFMPVQVPNDEEKNDP VLFANKVRNLMAEALGIPVT DHTYEDCRLMISAGQLTLPM EAGLVEFTKISRKLKLDWDG VRKHLDEYASIASSSKGGRI GIEEFAKYLKLPVSDVLRQ |
| Function | Exhibits both acyltransferase and acetyltransferase activities. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 2Lpc Acyltransferase 2Lpcat-2Lysopc Acyltransferase 21-Acylglycerol-3-Phosphate O-Acyltransferase 111-Agp Acyltransferase 111-Agpat 111-Acylglycerophosphocholine O-Acyltransferase1-Alkenylglycerophosphocholine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcetyl-Coa -Lyso-Platelet-Activating Factor AcetyltransferaseAcetyl-Coa -Lyso-Paf AcetyltransferaseLyso-Paf AcetyltransferaseLysopafatAcyltransferase-Like 1Lysophosphatidic Acid Acyltransferase AlphaLpaat-Alpha |
| Database Links | Reactome: R-HSA-1482788 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneCell MembraneLipid Droplet |
| Alternative Antibody Names | Anti-Lysophosphatidylcholine Acyltransferase 2 antibodyAnti-Lpc Acyltransferase 2 antibodyAnti-Lpcat-2 antibodyAnti-Lysopc Acyltransferase 2 antibodyAnti-1-Acylglycerol-3-Phosphate O-Acyltransferase 11 antibodyAnti-1-Agp Acyltransferase 11 antibodyAnti-1-Agpat 11 antibodyAnti-1-Acylglycerophosphocholine O-Acyltransferase antibodyAnti-1-Alkenylglycerophosphocholine O-Acyltransferase antibodyAnti-1-Alkylglycerophosphocholine O-Acetyltransferase antibodyAnti-Acetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase antibodyAnti-Acetyl-Coa -Lyso-Paf Acetyltransferase antibodyAnti-Lyso-Paf Acetyltransferase antibodyAnti-Lysopafat antibodyAnti-Acyltransferase-Like 1 antibodyAnti-Lysophosphatidic Acid Acyltransferase Alpha antibodyAnti-Lpaat-Alpha antibodyAnti-LPCAT2 antibodyAnti-AGPAT11 antibodyAnti-AYTL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
