Anti-LMAN1 antibody (1-100) [S2MR] (STJ11102202)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal LMAN1 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S2MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LMAN1 |
| Gene ID | 3998 |
| Uniprot ID | LMAN1_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MAGSRQRGLRARVRPLFCAL LLSLGRFVRGDGVGGDPAVA LPHRRFEYKYSFKGPHLVQS DGTVPFWAHAGNAIPSSDQI RVAPSLKSQRGSVWTKTKAA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LMAN1 (P49257). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | The N-terminal may be partly blocked. |
| Function | Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. |
| Protein Name | Protein Ergic-53Er-Golgi Intermediate Compartment 53 Kda ProteinGp58Intracellular Mannose-Specific Lectin Mr60Lectin Mannose-Binding 1 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013408Reactome: R-HSA-9013423Reactome: R-HSA-948021 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type I Membrane ProteinGolgi Apparatus MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Protein Ergic-53 antibodyAnti-Er-Golgi Intermediate Compartment 53 Kda Protein antibodyAnti-Gp58 antibodyAnti-Intracellular Mannose-Specific Lectin Mr60 antibodyAnti-Lectin Mannose-Binding 1 antibodyAnti-LMAN1 antibodyAnti-ERGIC53 antibodyAnti-F5F8D antibody |
Information sourced from Uniprot.org