Anti-LLGL2 antibody (938-1027) (STJ115286)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LLGL2 (938-1027) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Llgl2 |
| Gene ID | 217325 |
| Uniprot ID | L2GL2_MOUSE |
| Immunogen Region | 938-1027 |
| Immunogen Sequence | DSTKAKKHNRPSNGNGTGLK MTSSGHVRNSKSQSDGDEKK PGPVMEHALLNDAWVLKEIQ STLEGDRRSYGNWHPHRVAV GCRLSNGEAE |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 938-1027 of mouse LLGL2 (NP_663413.2). |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex. |
| Function | Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. |
| Protein Name | Llgl Scribble Cell Polarity Complex Component 2Lethal Giant Larvae-Like Protein 2Lethal(2 Giant Larvae Protein Homolog 2 |
| Database Links | |
| Cellular Localisation | CytoplasmLocalized In The Perinuclear Structure And Faintly At The Cell-Cell Contacts Sites In The InterphaseLocalized At The Cell Periphery During MetaphaseCortical Localization In Mitotic Cells |
| Alternative Antibody Names | Anti-Llgl Scribble Cell Polarity Complex Component 2 antibodyAnti-Lethal Giant Larvae-Like Protein 2 antibodyAnti-Lethal(2 Giant Larvae Protein Homolog 2 antibodyAnti-Llgl2 antibodyAnti-Llglh2 antibody |
Information sourced from Uniprot.org