| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LIM domain-binding protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LDB1 |
| Gene ID: |
8861 |
| Uniprot ID: |
LDB1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of LDB1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human LDB1 |
| Post Translational Modifications | Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome. |
| Function | Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state. |
| Protein Name | Lim Domain-Binding Protein 1Ldb-1Carboxyl-Terminal Lim Domain-Binding Protein 2Clim-2Lim Domain-Binding Factor Clim2Hldb1Nuclear Lim Interactor |
| Database Links | Reactome: R-HSA-8939236Reactome: R-HSA-9010553Reactome: R-HSA-9733709Reactome: R-HSA-9752946 |
| Cellular Localisation | NucleusColocalizes With Slk At Leading Edges |
| Alternative Antibody Names | Anti-Lim Domain-Binding Protein 1 antibodyAnti-Ldb-1 antibodyAnti-Carboxyl-Terminal Lim Domain-Binding Protein 2 antibodyAnti-Clim-2 antibodyAnti-Lim Domain-Binding Factor Clim2 antibodyAnti-Hldb1 antibodyAnti-Nuclear Lim Interactor antibodyAnti-LDB1 antibodyAnti-CLIM2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
