| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Histone-lysine N-methyltransferase 2C is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KMT2C |
| Gene ID: |
58508 |
| Uniprot ID: |
KMT2C_HUMAN |
| Specificity: |
This antibody detects endogenous levels of KMT2C at Human |
| Immunogen: |
Synthesized peptide derived from human KMT2C |
| Function | Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2D in enriching H3K4me1 mark on primed and active enhancer elements. |
| Protein Name | Histone-Lysine N-Methyltransferase 2cLysine N-Methyltransferase 2cHomologous To Alr ProteinMyeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 |
| Database Links | Reactome: R-HSA-3214841Reactome: R-HSA-5617472Reactome: R-HSA-8936459Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase 2c antibodyAnti-Lysine N-Methyltransferase 2c antibodyAnti-Homologous To Alr Protein antibodyAnti-Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3 antibodyAnti-KMT2C antibodyAnti-HALR antibodyAnti-KIAA1506 antibodyAnti-MLL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
